Laboratory Manager

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Caitlin Shepard
Email: caitlin.n.knowlton@emory.edu

Caitlin Shepard’s CV

Publications:

  • White TE, Brandariz-Nuñez A, Martinez-Lopez A, et al. A SAMHD1 mutation associated with Aicardi-Goutières Syndrome uncouples the ability of SAMHD1 to restrict HIV-1 from its ability to down modulate type I interferon in humans. Hum Mutat. 2017.
  • Bloch N, Gläsker S, Sitaram P, et al. A Highly Active Isoform of Lentivirus Restriction Factor SAMHD1 in Mouse. J Bio Chem. 2017.
  • Anacker DC, Aloor HL, Shepard CN, et al. HPV31 utilizes the ATR-Chk1 pathway to maintain elevated RRM2 levels and a replication-competent environment in differentiating Keratinocytes. Virology. 2016.
  • Opp S, Fricke T, Shepard C, et al. The small-molecule 3G11 inhibits HIV-1 reverse transcription. Chem Biol Drug Des. 2016.
  • Antonucci JM, St Gelais C, de Silva S, et al. SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity. Nature medicine. 2016.
  • Bhattacharya A, Wang Z, White T, et al. Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect. Scientific Reports. 2016.
  • Sommer AFR, Rivière L, Qu B, et al. Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle. Scientific Reports. 2016.
  • Bonifati S, Daly MB, St Gelais C, et al. SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells. Virology. 2016.
  • Wang F, St. Gelais C, de Silva S, et al. Phosphorylation of mouse SAMHD1 regulates its restriction of human immunodeficiency virus type 1 infection, but not murine leukemia virus infection. Virology. 2016.
  • Li D, Schlaepfer E, Audigé A, et al. Vpx mediated degradation of SAMHD1 has only a very limited effect on lentiviral transduction rate in ex vivo cultured HSPCs. Stem cell research. 2015.
  • Stevaert A, Nurra S, Pala N, et al. ­­­­­An integrated biological approach to guide the development of metal-chelating inhibitors of influenza virus PA endonuclease. Mol Pharmacol. 2015.
  • White TE, Brandariz-Nuñez A, Valle-Casuso JC, et al. Effects of human SAMHD1 Polymorphisms on HIV-1 Susceptibility. Virology. 2014.
  • Brandariz-Nuñez A, Valle-Casuso JC, White TE, et al. Contribution of oligomerization to the anti-HIV-1 properties of SAMHD1. Retrovirology. 2013.
  • Knowlton C, Veerapaneni R, D’Elia T, Rogers SO. Microbial Analyses of Ancient Ice Core Sections from Greenland and Antarctica. Biology. 2013.